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hýbat se Bezcenný Vařte lin et al 2017 bioorganic med chem nf kappa b chytrý Užitečný Buďte odrazováni

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone  Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and  Preliminary Exploration | Journal of Medicinal Chemistry
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration | Journal of Medicinal Chemistry

Drug Discovery: Covalent Bonds Between Small Molecules & Proteins
Drug Discovery: Covalent Bonds Between Small Molecules & Proteins

Bioorganic & Medicinal Chemistry Letters | Vol 27, Issue 3, Pages 361-700  (1 February 2017) | ScienceDirect.com by Elsevier
Bioorganic & Medicinal Chemistry Letters | Vol 27, Issue 3, Pages 361-700 (1 February 2017) | ScienceDirect.com by Elsevier

Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase  Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory  Diseases | Journal of Medicinal Chemistry
Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases | Journal of Medicinal Chemistry

Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes  for the Kappa Opioid Receptor | Journal of Medicinal Chemistry
Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor | Journal of Medicinal Chemistry

Design of Novel 3-Pyrimidinylazaindole CDK2/9 Inhibitors with Potent In  Vitro and In Vivo Antitumor Efficacy in a Triple-Negative Breast Cancer  Model | Journal of Medicinal Chemistry
Design of Novel 3-Pyrimidinylazaindole CDK2/9 Inhibitors with Potent In Vitro and In Vivo Antitumor Efficacy in a Triple-Negative Breast Cancer Model | Journal of Medicinal Chemistry

Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor |  Journal of Medicinal Chemistry
Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor | Journal of Medicinal Chemistry

Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A  Medicinal Chemistry Perspective | Journal of Medicinal Chemistry
Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective | Journal of Medicinal Chemistry

Bioorganic & Medicinal Chemistry | Vol 10, Issue 12, Pages 3695-4194  (December 2002) | ScienceDirect.com by Elsevier
Bioorganic & Medicinal Chemistry | Vol 10, Issue 12, Pages 3695-4194 (December 2002) | ScienceDirect.com by Elsevier

Discovery of Novel Small-Molecule Inhibitors of NF-κB Signaling with  Antiinflammatory and Anticancer Properties | Journal of Medicinal Chemistry
Discovery of Novel Small-Molecule Inhibitors of NF-κB Signaling with Antiinflammatory and Anticancer Properties | Journal of Medicinal Chemistry

Synthetic Approaches to the New Drugs Approved During 2017 | Journal of Medicinal  Chemistry
Synthetic Approaches to the New Drugs Approved During 2017 | Journal of Medicinal Chemistry

Protein‐Templated Fragment Ligations—From Molecular Recognition to Drug  Discovery - Jaegle - 2017 - Angewandte Chemie International Edition - Wiley  Online Library
Protein‐Templated Fragment Ligations—From Molecular Recognition to Drug Discovery - Jaegle - 2017 - Angewandte Chemie International Edition - Wiley Online Library

4‐(Di‐/Trifluoromethyl)‐2‐heterabicyclo[2.1.1]hexanes: Advanced Fluorinated  Phenyl Isosteres and Proline analogues - Homon - 2021 - European Journal of  Organic Chemistry - Wiley Online Library
4‐(Di‐/Trifluoromethyl)‐2‐heterabicyclo[2.1.1]hexanes: Advanced Fluorinated Phenyl Isosteres and Proline analogues - Homon - 2021 - European Journal of Organic Chemistry - Wiley Online Library

Medicinal chemistry of indole derivatives: Current to future therapeutic  prospectives - ScienceDirect
Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives - ScienceDirect

Discovery and Optimization of Boronic Acid Based Inhibitors of Autotaxin |  Journal of Medicinal Chemistry
Discovery and Optimization of Boronic Acid Based Inhibitors of Autotaxin | Journal of Medicinal Chemistry

Molecules | Free Full-Text | Synthesis and Evaluation of NF-κB  Inhibitory Activity of Mollugin Derivatives
Molecules | Free Full-Text | Synthesis and Evaluation of NF-κB Inhibitory Activity of Mollugin Derivatives

The Cravatt Lab
The Cravatt Lab

Molecules | Free Full-Text | 2-Phenethylamines in Medicinal Chemistry: A  Review
Molecules | Free Full-Text | 2-Phenethylamines in Medicinal Chemistry: A Review

Molecules | Free Full-Text | Anti-Cancer Potential of Synthetic Oleanolic  Acid Derivatives and Their Conjugates with NSAIDs
Molecules | Free Full-Text | Anti-Cancer Potential of Synthetic Oleanolic Acid Derivatives and Their Conjugates with NSAIDs

Molecules | Free Full-Text | Chemistry and the Potential Antiviral,  Anticancer, and Anti-Inflammatory Activities of Cardiotonic Steroids  Derived from Toads
Molecules | Free Full-Text | Chemistry and the Potential Antiviral, Anticancer, and Anti-Inflammatory Activities of Cardiotonic Steroids Derived from Toads

Fluorine and Fluorinated Motifs in the Design and Application of  Bioisosteres for Drug Design | Journal of Medicinal Chemistry
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design | Journal of Medicinal Chemistry

Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors  That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal  of Medicinal Chemistry
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal of Medicinal Chemistry

Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry  Perspective | Journal of Medicinal Chemistry
Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective | Journal of Medicinal Chemistry

Molecules | Free Full-Text | Chlojaponilactone B Attenuates  Lipopolysaccharide-Induced Inflammatory Responses by Suppressing  TLR4-Mediated ROS Generation and NF-κB Signaling Pathway
Molecules | Free Full-Text | Chlojaponilactone B Attenuates Lipopolysaccharide-Induced Inflammatory Responses by Suppressing TLR4-Mediated ROS Generation and NF-κB Signaling Pathway